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References and Resources for Chapter 2: Unrestricted Kangaroo Care in the NICU

The following references and resources support the evidence base for Unrestricted Kangaroo Care (uKC). They are organized by topic to guide clinicians, administrators, and families in expanding access and sustaining safe practice.

  • Global Standards

    • WHO guidelines¹

    • Infant and Family-Centered Developmental Care Standards, Competencies, and Recommended Best Practices²–⁴

    • European Standards of Care for Newborn Health⁵,⁶

  • Growth and Neurodevelopment

    • Evidence linking KC to improved infant growth and brain development⁷

  • Milk Production and Breastfeeding

    • Studies showing KC improves milk supply, breastfeeding initiation, and exclusivity⁸–¹³

  • Physiologic Stability

    • Preterm infant regulation of temperature, oxygenation, and vital signs¹⁴

  • Clinical Outcomes

    • Reduced morbidity, mortality, sepsis, and NICU length of stay¹⁵,¹⁶

  • Parental Health

    • Maternal and paternal mental health and well-being benefits¹⁷

  • Safety Considerations

    • Risks to monitor include:

      • Accidental falls¹⁸–²⁰

      • Sudden unexpected postnatal collapse²¹,²²

      • Dislodgement of equipment or unplanned extubation²³–²⁵

  • KC in Complex and Critically Ill Infants

    • Increasing evidence supports KC for:

      • Extremely low birth weight infants²⁶–³⁶

      • Intubated infants³³,³⁵,³⁷–³⁹

      • Surgical infants⁴⁰,⁴¹

      • Infants with central lines⁴²

  • Barriers and Risk Management

    • Barriers to KC⁴³–⁴⁷

    • Evidence-based strategies for risk management⁴⁸–⁵⁰

 

48. Weber AM, Jackson YC, Elder MR, et al. Application of a Risk Management Framework to Parent Sleep During Skin-to-Skin Care in the NICU. J Obstet Gynecol Neonatal Nurs JOGNN. 2022;51(3):336-348. doi:10.1016/j.jogn.2022.02.004  https://pubmed.ncbi.nlm.nih.gov/35288109/

49.      Weber A, Elder M, Voos KC, Lambert JW, Kaplan HC, Jackson YC. Clinician Opinions and Approaches to Manage Risk Related to Safe Sleep During Skin-to-Skin Care. J Obstet Gynecol Neonatal Nurs JOGNN. 2020;49(5):464-474. doi:10.1016/j.jogn.2020.07.001  https://pubmed.ncbi.nlm.nih.gov/32726581/

50.      Weber A, Jackson Y. A Survey of Neonatal Clinicians’ Use, Needs, and Preferences for Kangaroo Care Devices. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2021;21(3):232-241. doi:10.1097/ANC.0000000000000790  https://pubmed.ncbi.nlm.nih.gov/32858546/ 

 

REFERENCES

1.         World Health Organization. Kangaroo Mother Care: Implementation Strategy for Scale-up Adaptable to Different Country Contexts. World Health Organization; 2023. Accessed May 22, 2023. https://apps.who.int/iris/handle/10665/367625

2.         Phillips R, Smith K, First Consensus Conference on Standards, Competencies and Recommended Best Practices for Infant and Family Centered Developmental Care in the Intensive Care Unit. IFCDC- Recommendations for Skin-to-Skin Contact with Intimate Family Members. NICU Recommended Standards. 2020. Accessed March 17, 2020. https://nicudesign.nd.edu/nicu-care-standards/ifcdc--recommendations-for-skin-to-skin-contact-with-intimate-family-members/

3.         Browne JV, Jaeger CB, Kenner C, Gravens Consensus Committee on Infant and Family Centered Developmental Care. Executive summary: standards, competencies, and recommended best practices for infant- and family-centered developmental care in the intensive care unit. J Perinatol Off J Calif Perinat Assoc. 2020;40(Suppl 1):5-10. doi:10.1038/s41372-020-0767-1

4.         Browne JV, Jaeger CB, Arvedson JC, et al. Developmental Care Standards for Infants in Intensive Care.; 2020:1-139. Accessed March 17, 2020. https://nicudesign.nd.edu/nicu-care-standards/

5.         Bergman NJ, Westrup B, Kuhn P, et al. Infant- & family-centered developmental care: Very early and continuous skin-to-skin contact. In: European Standards of Care for Newborn Health (ESCNH). European Standards of Care for Newborn Health; 2018. Accessed May 7, 2025. https://newborn-health-standards.org/standards/standards-english/infant-family-centred-developmental-care/very-early-and-continuous-skin-to-skin-contact/

6.         Lindacher V, Altebaeumer P, Marlow N, et al. European Standards of Care for Newborn Health-A project protocol. Acta Paediatr Oslo Nor 1992. 2021;110(5):1433-1438. doi:10.1111/apa.15712

7.         Han Z, Li X, Hu F, Yang J. Meta-analysis of the Impact of Kangaroo Care on Physical Growth and Neurobehavioral Development in Premature Infants. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2025;25(2):162-172. doi:10.1097/ANC.0000000000001254

8.         Jayaraman D, Mukhopadhyay K, Bhalla AK, Dhaliwal LK. Randomized Controlled Trial on Effect of Intermittent Early Versus Late Kangaroo Mother Care on Human Milk Feeding in Low-Birth-Weight Neonates. J Hum Lact Off J Int Lact Consult Assoc. 2017;33(3):533-539. doi:10.1177/0890334416685072

9.         Sinha B, Mazumder S, Thakur A, et al. Effect of kangaroo mother care in low birth weight infants on human milk intake: a randomized controlled trial. Am J Clin Nutr. 2025;121(5):1109-1116. doi:10.1016/j.ajcnut.2025.02.006

10.      Daniels F, Sawangkum A, Kumar A, Coombs K, Louis-Jacques A, Ho TTB. Skin to Skin Contact Correlated with Improved Production and Consumption of Mother’s Own Milk. Breastfeed Med Off J Acad Breastfeed Med. 2023;18(6):483-488. doi:10.1089/bfm.2022.0297

11.      Mekonnen AG, Yehualashet SS, Bayleyegn AD. The effects of kangaroo mother care on the time to breastfeeding initiation among preterm and LBW infants: a meta-analysis of published studies. Int Breastfeed J. 2019;14:12. doi:10.1186/s13006-019-0206-0

12.      Anstey E, Noiman A, Boundy E, Nelson J. Maternity care practices supportive of breastfeeding in U.S. advanced neonatal care units, United States, 2022. J Perinatol Off J Calif Perinat Assoc. 2024;44(11):1560-1566. doi:10.1038/s41372-024-02139-3

13.      Wang Y, Zhao T, Zhang Y, Li S, Cong X. Positive Effects of Kangaroo Mother Care on Long-Term Breastfeeding Rates, Growth, and Neurodevelopment in Preterm Infants. Breastfeed Med Off J Acad Breastfeed Med. 2021;16(4):282-291. doi:10.1089/bfm.2020.0358

14.      Zengin H, Suzan OK, Hur G, Kolukısa T, Eroglu A, Cinar N. The effects of kangaroo mother care on physiological parameters of premature neonates in neonatal intensive care unit: A systematic review. J Pediatr Nurs. Published online May 4, 2023:S0882-5963(23)00094-5. doi:10.1016/j.pedn.2023.04.010

15.      WHO Immediate KMC Study Group, Arya S, Naburi H, et al. Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight. N Engl J Med. 2021;384(21):2028-2038. doi:10.1056/NEJMoa2026486

16.      Zhu Z, Wang X, Chen W, et al. The efficacy of Kangaroo-Mother care to the clinical outcomes of LBW and premature infants in the first 28 days: A meta-analysis of randomized clinical trials. Front Pediatr. 2023;11:1067183. doi:10.3389/fped.2023.1067183

17.      Pathak BG, Sinha B, Sharma N, Mazumder S, Bhandari N. Effects of kangaroo mother care on maternal and paternal health: systematic review and meta-analysis. Bull World Health Organ. 2023;101(6):391-402G. doi:10.2471/BLT.22.288977

18.      Monson SA, Henry E, Lambert DK, Schmutz N, Christensen RD. In-hospital falls of newborn infants: data from a multihospital health care system. Pediatrics. 2008;122(2):e277-280. doi:10.1542/peds.2007-3811

19.      Matteson T, Henderson-Williams A, Nelson J. Preventing in-hospital newborn falls: a literature review. MCN Am J Matern Child Nurs. 2013;38(6):359-366; quiz 367-368. doi:10.1097/NMC.0b013e3182a1fb91

20.      Feldman-Winter L, Goldsmith JP, COMMITTEE ON FETUS AND NEWBORN, TASK FORCE ON SUDDEN INFANT DEATH SYNDROME. Safe Sleep and Skin-to-Skin Care in the Neonatal Period for Healthy Term Newborns. Pediatrics. 2016;138(3). doi:10.1542/peds.2016-1889

21.      Davanzo R, De Cunto A, Paviotti G, et al. Making the first days of life safer: preventing sudden unexpected postnatal collapse while promoting breastfeeding. J Hum Lact Off J Int Lact Consult Assoc. 2015;31(1):47-52. doi:10.1177/0890334414554927

22.      Shipstone R, Young J, Kearney L. New Frameworks for Understanding Sudden Unexpected Deaths in Infancy (SUDI) in Socially Vulnerable Families. J Pediatr Nurs Nurs Care Child Fam. 2017;37:35-41. doi:10.1016/j.pedn.2017.06.022

23.      Silva PSL da, Reis ME, Aguiar VE, Fonseca MCM. Unplanned extubation in the neonatal ICU: a systematic review, critical appraisal, and evidence-based recommendations. Respir Care. 2013;58(7):1237-1245. doi:10.4187/respcare.02164

24.      Ludington-Hoe SM, Ferreira C, Swinth J, Ceccardi JJ. Safe criteria and procedure for kangaroo care with intubated preterm infants. J Obstet Gynecol Neonatal Nurs JOGNN NAACOG. 2003;32(5):579-588.

25.      Azevedo VMG de O, Xavier CC, Gontijo F de O. Safety of Kangaroo Mother Care in intubated neonates under 1500 g. J Trop Pediatr. 2012;58(1):38-42. doi:10.1093/tropej/fmr033

26.      Nation H, Sanlorenzo L, Lebar K, Brandon D. A Quality Improvement Project to Increase Frequency of Skin-to-Skin Contact for Extreme Low-Birth-Weight Infants in the Neonatal Intensive Care Unit. J Perinat Neonatal Nurs. 2021;35(3):247-257. doi:10.1097/JPN.0000000000000556

27.      Fathi O, Nelin LD, Shepherd EG, Reber KM. Development of a small baby unit to improve outcomes for the extremely premature infant. J Perinatol Off J Calif Perinat Assoc. 2022;42(2):157-164. doi:10.1038/s41372-021-00984-0

28.      Collados-Gómez L, Esteban-Gonzalo L, López-López C, et al. Lateral Kangaroo Care in Hemodynamic Stability of Extremely Preterm Infants: Protocol Study for a Non-Inferiority Randomized Controlled Trial CANGULAT. Int J Environ Res Public Health. 2022;19(1):293. doi:10.3390/ijerph19010293

29.      Sharma D, Murki S, Pratap OT. To compare growth outcomes and cost-effectiveness of “Kangaroo ward care” with “intermediate intensive care” in stable extremely low birth weight infants: randomized control trial. J Matern Fetal Neonatal Med. 2017;30(14):1659-1665. doi:10.1080/14767058.2016.1220531

30.      Span LC, van Dokkum NH, Ravensbergen AG, Bos AF, Jaschke AC. Combining Kangaroo Care and Live-Performed Music Therapy: Effects on Physiological Stability and Neurological Functioning in Extremely and Very Preterm Infants. Int J Environ Res Public Health. 2021;18(12):6580. doi:10.3390/ijerph18126580

31.      Obaid M, Igawa T, Maxwell A, et al. “Liquid Gold” Lactation Bundle and Breastfeeding Rates in Racially Diverse Mothers of Extremely Low-Birth-Weight Infants. Breastfeed Med Off J Acad Breastfeed Med. 2021;16(6):463-470. doi:10.1089/bfm.2020.0322

32.      Khanam S, Khan J, Sharma D, Chawla D, Murki S. Nutritional bundle to improve growth outcomes among very low birth weight infants. J Matern-Fetal Neonatal Med Off J Eur Assoc Perinat Med Fed Asia Ocean Perinat Soc Int Soc Perinat Obstet. 2015;28(15):1851-1855. doi:10.3109/14767058.2014.970528

33.      Pavlek LR, Mueller C, Jebbia MR, et al. Perspectives on developing and sustaining a small baby program. Semin Perinatol. 2022;46(2):151548. doi:10.1016/j.semperi.2021.151548

34.      Xie X, Chen X, Sun P, et al. Kangaroo Mother Care Reduces Noninvasive Ventilation and Total Oxygen Support Duration in Extremely Low Birth Weight Infants. Am J Perinatol. 2021;38(8):791-795. doi:10.1055/s-0039-3402717

35.      Bisanalli S, Nesargi S, Govindu RM, Rao SP. Kangaroo Mother Care in Hospitalized Low Birth-Weight Infants on Respiratory Support: A Feasibility and Safety Study. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2019;19(6):E21-E25. doi:10.1097/ANC.0000000000000666

36.      Lorenz L, Dawson JA, Jones H, et al. Skin-to-skin care in preterm infants receiving respiratory support does not lead to physiological instability. Arch Dis Child Fetal Neonatal Ed. 2017;102(4):F339-F344. doi:10.1136/archdischild-2016-311752

37.      Melton K, Ryan C, Saunders A, Zix J. Reducing Pediatric Unplanned Extubation Across Multiple ICUs Using Quality Improvement. Pediatrics. 2022;149(5):e2021052259. doi:10.1542/peds.2021-052259

38.      Klugman D, Melton K, Maynord PO, et al. Assessment of an Unplanned Extubation Bundle to Reduce Unplanned Extubations in Critically Ill Neonates, Infants, and Children. JAMA Pediatr. 2020;174(6):e200268. doi:10.1001/jamapediatrics.2020.0268

39.      Marvin MM, Gardner FC, Sarsfield KM, Travagli RA, Doheny KK. Increased Frequency of Skin-to-Skin Contact Is Associated with Enhanced Vagal Tone and Improved Health Outcomes in Preterm Neonates. Am J Perinatol. 2019;36(5):505-510. doi:10.1055/s-0038-1669946

40.      Levesque V, Johnson K, McKenzie A, Nykipilo A, Taylor B, Joynt C. Implementing a Skin-to-Skin Care and Parent Touch Initiative in a Tertiary Cardiac and Surgical Neonatal Intensive Care Unit. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2021;21(2):E24-E34. doi:10.1097/ANC.0000000000000770

41.      Kelley-Quon LI, Kenney BD, Bartman T, et al. Safety and feasibility of skin-to-skin care for surgical infants: A quality improvement project. J Pediatr Surg. 2019;54(11):2428-2434. doi:10.1016/j.jpedsurg.2019.02.016

42.      Catherine ZG, Béatrice P, Fabrice L, Claire H, Alain D. Skin-to-skin contact with an umbilical venous catheter: prospective evaluation in a level 3 unit. Eur J Pediatr. 2016;175(4):551-555. doi:10.1007/s00431-015-2665-7

43.      Fluharty M, Nemeth LS, Logan A, Nichols M. What Do Neonatal Intensive Care Unit Policies Tell Us About Kangaroo Care implementation? A Realist Review. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2021;21(4):E76-E85. doi:10.1097/ANC.0000000000000808

44.      Chan GJ, Labar AS, Wall S, Atun R. Kangaroo mother care: a systematic review of barriers and enablers. Bull World Health Organ. 2016;94(2):130-141J. doi:10.2471/BLT.15.157818

45.      Smith ER, Bergelson I, Constantian S, Valsangkar B, Chan GJ. Barriers and enablers of health system adoption of kangaroo mother care: a systematic review of caregiver perspectives. BMC Pediatr. 2017;17(1):35. doi:10.1186/s12887-016-0769-5

46.      Hull WL, Gongora P. Implementing Early Kangaroo Mother Care: A Quality Improvement Initiative. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2025;25(1):46-54. doi:10.1097/ANC.0000000000001231

47.      Beaumont L, Mullaney D, Eklund W, DeGrazia M. Kangaroo Care in the Neonatal Intensive Care Unit-A Practice Change Initiative. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2025;25(2):129-137. doi:10.1097/ANC.0000000000001252

48.      Weber AM, Jackson YC, Elder MR, et al. Application of a Risk Management Framework to Parent Sleep During Skin-to-Skin Care in the NICU. J Obstet Gynecol Neonatal Nurs JOGNN. 2022;51(3):336-348. doi:10.1016/j.jogn.2022.02.004

49.      Weber A, Elder M, Voos KC, Lambert JW, Kaplan HC, Jackson YC. Clinician Opinions and Approaches to Manage Risk Related to Safe Sleep During Skin-to-Skin Care. J Obstet Gynecol Neonatal Nurs JOGNN. 2020;49(5):464-474. doi:10.1016/j.jogn.2020.07.001

50.      Weber A, Jackson Y. A Survey of Neonatal Clinicians’ Use, Needs, and Preferences for Kangaroo Care Devices. Adv Neonatal Care Off J Natl Assoc Neonatal Nurses. 2021;21(3):232-241. doi:10.1097/ANC.0000000000000790

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